Vitamin C Research Today is a free monthly online journal that collates and summarizes the latest research about Vitamin C, including details on benefits, dosage, supplements, information.

Selective response of dopamine in the presence of ascorbic acid at multi-walled carbon nanotube modified gold electrode.

Zhang P, Wu FH, Zhao GC, Wei XW

School of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, P. R. China.

The acid-treated multi-walled carbon nanotubes (MWNTs), which were modified on the surface of gold electrode, offers substantial improvements in voltammetric sensitivity and selectivity towards the determination of dopamine (DA). It can inhibit the voltammetric response of ascorbic acid (AA) while the redox reaction of dopamine is promoted. When a differential pulse voltammetric (DPV) technique was used, the peak separation between DAs and AAs was 244 mV. Based on this, a selective method could be constructed to detect DA in the presence of 1,000 times higher concentration of AA. The effect of various experimental parameters on the voltammetric response of dopamine was investigated. Under the chosen conditions, the peak currents are correspondent linearly to the concentrations of DA in the range of 5 x 10(-7) approximately 4 x 10(-4) mol L(-1) with a limit of detection of 2 x 10(-7) mol L(-1). The proposed method can be applied to detect DA in real samples.

Published 21 June 2005 in Bioelectrochemistry, 67(1): 109-14.
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