Vitamin C Research Today is a free monthly online journal that collates and summarizes the latest research about Vitamin C, including details on benefits, dosage, supplements, information. | ||||||||
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Dietary high protein and vitamin C mitigates endosulfan toxicity in the spotted murrel, Channa punctatus (Bloch, 1793).Sarma K, Pal AK, Sahu NP, Ayyappan S, Baruah K Division of Fisheries Science, Central Agricultural Research Institute, ICAR, Port Blair 744101, India. The amelioration effect of dietary high protein and vitamin C against stress was evaluated in spotted murrel, Channa punctatus, exposed to endosulfan. Two hundred and forty fish (average weight: 27.01 g/fish), distributed equally into 4 different groups (control, T(1), T(2), and T(3)), each with 6 replicates were fed with control (40% crude protein, CP and 0.1% vitamin C), T(1) (40% CP and 0.1% vitamin C), T(2) (50% CP and 0.1% vitamin C), and T(3) (50% CP and 0.2% vitamin C) diets for 90 days. Groups fed T(1), T(2), and T(3) diets were exposed to sublethal endosulfan concentration, whereas the control was maintained without endosulfan exposure. Results indicated significant reduction in the growth performance, survival, and activities of lactate dehydrogenase (liver and muscle), malate dehydrogenase (liver and muscle), enzymes of protein metabolism (aspartate amino transferase in liver and alanine amino transferase in liver and muscle), acetyl choline esterase (brain), alkaline phosphatase activity (liver), and ATPase (gill) enzymes of group fed control diet and exposed to endosulfan. However, endosulfan exposed fish fed high CP and vitamin C diet exhibited significant (P<0.05) improvement in their growth performance and metabolic enzyme activities. Further, high CP and vitamin C diet reduced endosulfan accumulation in the muscle. Overall results indicate that vitamin C (0.2%) supplementation in high CP (50%) diet improves growth, metabolism, and reduce endosulfan bioaccumulation in C. punctatus. Published 28 April 2009 in Sci Total Environ, 407(12): 3668-73.
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